Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1179 | Male Reproduction | ECE2017

Leptin modulates Sertoli cells mitochondrial function and biogenesis with implications for the nutritional support of spermatogenesis

Moreira Bruno M , D Martins Ana , Monteiro Mariana P , Sousa Mario , Alves Marco G , Oliveira Pedro F

Current lifestyle, characterized by physical inactivity and a poor diet, is heavily linked with an increased incidence of metabolic diseases. One of the most serious silent co-morbidities of those diseases is infertility. The hormonal link between food intake and energy homeostasis is mediated by the leptin ghrelin axis. Compelling evidence suggests that direct leptin’s action regulates cellular glucose homeostasis and mitochondrial biogenesis. We have recently shown that...